Your participation in the Knight Alzheimer’s Primary Prevention Challenge will support the first-ever primary prevention trial for Alzheimer’s and help Washington University lead the fight against this devastating disease.

Clinical trials are essential tools that will help us learn how to prevent Alzheimer’s disease or delay its age of onset. Your support for the Knight Family DIAN-TU Challenge will help researchers gain critical insight into the causes of Alzheimer’s disease and develop better methods of diagnosis, treatment, and prevention.


About the Challenge

woman helping a senior walk

The Knight Alzheimers Primary Prevention Challenge is a matching-gift opportunity that doubles the impact of contributions to support the DIAN-TU primary prevention clinical trial.

What is DIAN-TU?

doctor reviewing brain scans

The Knight Family DIAN-TU has taken a leading role in the research of Alzheimer’s-associated brain changes that begin a decade or more before symptoms appear.

DIAN-TU Leadership

healthcare worker helping a person prepare for MRI

Meet the internationally recognized scientists and physicians who lead the clinical research arm of the Dominantly Inherited Alzheimer Network.


Did you know?

Alzheimer’s disease is the only major cause of death in the U.S. for which there is no prevention or effective treatment.

Medical advancement

William ArvinMSC 1247-HAN-900
101 South Hanley, Suite 900
St. Louis, Missouri 63105